| DOE N 251.107PDF | Cancellation of DOE O 1450.4 | Archive | IM - Office of the Chief Information Officer | Sep 26, 2011 |
| DOE N 251.108PDF | Cancellation of DOE O 540.1B | Archive | MA - Office of Management | Oct 25, 2011 |
| DOE N 251.109PDF | Cancellation of DOE G 413.3-11 | Archive | MA - Office of Management | Nov 9, 2011 |
| DOE N 251.11PDF | Cancellation of Directives | Archive | NN - Office of Arms Control and Nonproliferation | Feb 13, 1996 |
| DOE N 251.110PDF | Cancellation of Guide | Archive | MA - Office of Management | Dec 22, 2011 |
| DOE N 251.111PDF | Cancellation of DOE O 482.1 | Archive | SC - Office of Science | Feb 10, 2012 |
| DOE N 251.112PDF | Cancellation of DOE M 200.1-1 Chapter 9 | Archive | HS - Office of Health, Safety and Security | Dec 27, 2013 |
| DOE N 251.113PDF | Cancellation of Directives | Archive | NA - National Nuclear Security Administration | Jan 26, 2015 |
| DOE N 251.114PDF | Cancellation of Directive | Archive | MA - Office of Management | Mar 4, 2016 |
| DOE N 251.115PDF | Cancellation of Directives | Archive | MA - Office of Management | May 10, 2016 |
| DOE N 251.116PDF | Cancellation of Directives | Archive | MA - Office of Management | May 26, 2016 |
| DOE N 251.117PDF | Cancellation of Directives | Archive | AU - Office of Environment, Health, Safety and Security | Aug 9, 2016 |
| DOE N 251.118PDF | Cancellation of Directives | Archive | MA - Office of Management | Jan 17, 2017 |
| DOE N 251.119PDF | Cancellation of Directives | Archive | HC - Office of the Chief Human Capital Officer | Oct 20, 2017 |
| DOE N 251.12PDF | Cancellation of Directives | Archive | HR - Office of Human Resources | Jun 21, 1996 |
| DOE N 251.120PDF | Cancellation of Directive | Archive | MA - Office of Management | Jan 12, 2021 |
| DOE N 251.121PDF | Cancellation of Directive | Archive | MA - Office of Management | Jul 30, 2021 |
| DOE N 251.122PDF | Cancellation of DOE P 205.1, Departmental Cyber Security Management Policy | Archive | MA - Office of Management | Sep 23, 2021 |
| DOE N 251.123PDF | Cancellation of DOE O 542.2A, Unsolicited Proposals | Current | MA - Office of Management | Jul 28, 2023 |
| DOE N 251.124PDF | Cancellation of DOE O 350.5, COVID Safety Protocol for Federal Contractors | Current | MA - Office of Management | Aug 11, 2023 |
| DOE N 251.125PDF | Cancellation of DOE O 328.1, Human Capital Management Accountability Program and DOE O 329.2 Chg 1 (PgChg), Excepted Service Authority for Exceptionally Well Qualified (EWQ) Pay Plan | Current | MA - Office of Management | Oct 28, 2024 |
| DOE N 251.127 | Cancellation of DOE N 435.1, Contact-Handled and Remote-Handled Transuranic Waste Package | Current | MA - Office of Management | Aug 20, 2024 |
| DOE N 251.128 | Cancellation of DOE O 436.1A, Departmental Sustainability and DOE O 311.1B Chg. 1 (LtdChg), Equal Employment Opportunity and Diversity Program | Current | MA - Office of Management | Jan 30, 2025 |
| DOE N 251.13PDF | Cancellation of Directive | Archive | HG - Office of Hearings and Appeals | Jul 19, 1996 |
| DOE N 251.14PDF | Cancellation of Directive | Archive | PR - Office of Procurement Assistance and Program Management | Aug 5, 1996 |