| DOE G 414.1-1CPDF | Management and Independent Assessments Guide | Current | EH - Office of Environment, Health, Safety and Security | Mar 27, 2014 |
| DOE G 414.1-2B Chg 2 (Admin Chg)PDF | Quality Assurance Program Guide | Current | EH - Office of Environment, Health, Safety and Security | Aug 16, 2011 |
| DOE G 414.1-4PDF | Safety Software Guide for Use with 10 CFR 830, Subpart A, Quality Assurance Requirements, and DOE O 414.1C, Quality Assurance | Current | EH - Office of Environment, Health, Safety and Security | Jun 17, 2005 |
| DOE G 415.1-1PDF | Information Technology Project Execution Model Guide | Current | IM - Office of the Chief Information Officer | Jul 17, 2014 |
| DOE G 415.1-2PDF | Information Technology Project Execution Model Guide for Small and Medium Projects | Current | IM - Office of the Chief Information Officer | Dec 21, 2015 |
| DOE G 420.1-1APDF | Nonreactor Nuclear Safety Design Guide for use with DOE O 420.1C, Facility Safety | Current | EH - Office of Environment, Health, Safety and Security | Dec 4, 2012 |
| DOE G 420.2-1APDF | Accelerator Facility Safety Implementation Guide for DOE O 420.2C, Safety of Accelerator Facilities | Current | SC - Office of Science | Aug 1, 2014 |
| DOE G 421.1-2APDF | Implementation Guide for Use in Developing Documented Safety Analyses to Meet Subpart B of 10 CFR 830 | Current | EH - Office of Environment, Health, Safety and Security | Dec 19, 2011 |
| DOE G 423.1-1BPDF | Implementation Guide for Use in Developing Technical Safety Requirements | Current | EH - Office of Environment, Health, Safety and Security | Mar 18, 2015 |
| DOE G 424.1-1CPDF | Implementation Guide for Use in Addressing Unreviewed Safety Question Requirements | Current | EH - Office of Environment, Health, Safety and Security | Jul 27, 2022 |
| DOE G 430.1-1PDF | Cost Estimating Guide | Current | PM - Office of Project Management Oversight and Assessments | Mar 28, 1997 |
| DOE G 430.1-2PDF | Implementation Guide for Surveillance and Maintenance during Facility Transition and Disposition | Current | EM - Office of Environmental Management | Sep 29, 1999 |
| DOE G 430.1-3PDF | Deactivation Implementation Guide | Current | EM - Office of Environmental Management | Sep 29, 1999 |
| DOE G 430.1-4PDF | Decommissioning Implementation Guide | Current | EM - Office of Environmental Management | Sep 2, 1999 |
| DOE G 430.1-5PDF | Transition Implementation Guide | Current | EM - Office of Environmental Management | Apr 24, 2001 |
| DOE G 430.1-7PDF | Alternative Financing Guide | Current | MA - Office of Management | Mar 12, 2012 |
| DOE G 430.1-8PDF | Asset Revitalization Guide for Asset Management and Reuse | Current | LM - Office of Legacy Management | Jul 16, 2015 |
| DOE G 433.1-1A Chg 1 (Admin Chg)PDF | Nuclear Facility Maintenance Management Program Guide for Use with DOE O 433.1B | Current | EH - Office of Environment, Health, Safety and Security | Sep 9, 2011 |
| DOE G 436.1-1PDF | Federal Sustainable Print Management | Current | IM - Office of the Chief Information Officer | Nov 17, 2015 |
| DOE G 440.1-1B Chg 1 (Admin Chg)PDF | Worker Safety and Health Program for DOE (Including the National Nuclear Security Administration) Federal and Contractor Employees | Current | EH - Office of Environment, Health, Safety and Security | Oct 20, 2011 |
| DOE G 440.1-7A, Chg 1 (Admin Chg) | Implementation Guide for use with 10 CFR Part 850, Chronic Beryllium Disease Prevention Program | Current | EH - Office of Environment, Health, Safety and Security | Jan 4, 2001 |
| DOE G 441.1-1C Chg 1 (Admin Chg)PDF | Radiation Protection Programs Guide for Use with Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection | Current | EH - Office of Environment, Health, Safety and Security | May 19, 2008 |
| DOE G 444.1-1, Chg 1 (Admin Chg)PDF | Guide on Preventing and Responding to All Forms of Violence in the Workplace | Current | HC - Office of the Chief Human Capital Officer | Apr 22, 2015 |
| DOE G 450.4-1CPDF | Integrated Safety Management System Guide | Current | EH - Office of Environment, Health, Safety and Security | Sep 29, 2011 |
| DOE G 460.1-1PDF | Implementation Guide for Use with DOE O 460.1A, Packaging and Transportation Safety | Current | EM - Office of Environmental Management | Jun 5, 1997 |