| DOE P 443.1PDF | Protection of Human Subjects | Archive | SC - Office of Science | May 15, 2000 |
| DOE P 443.1APDF | Protection of Human Subjects | Archive | SC - Office of Science | Dec 20, 2007 |
| DOE P 444.1PDF | Preventing and Responding to all Forms of Violence in the Workplace | Archive | HC - Office of the Chief Human Capital Officer | Nov 6, 2014 |
| DOE P 444.1 Chg. 1 (AdminChg) | Preventing and Responding to all Forms of Violence in the Workplace | Current | HC - Office of the Chief Human Capital Officer | Nov 6, 2014 |
| DOE P 450.1PDF | Environment, Safety, and Health Policy for the Department of Energy Complex | Archive | EH - Office of Environment, Safety and Health | Jun 15, 1995 |
| DOE P 450.2PDF | Identification, Implementation and Compliance with Environment, Safety and Health Requirements | Archive | EH - Office of Environment, Safety and Health | Sep 29, 1995 |
| DOE P 450.2APDF | Identifying, Implementing and Complying with Environment, Safety and Health Requirements | Archive | HS - Office of Health, Safety and Security | May 15, 1996 |
| DOE P 450.3PDF | Authorizing Use of the Necessary and Sufficient Process for Standards-Based Environment, Safety and Health Management | Archive | HS - Office of Health, Safety and Security | Jan 25, 1996 |
| DOE P 450.4PDF | Safety Management System Policy | Archive | HS - Office of Health, Safety and Security | Oct 15, 1996 |
| DOE P 450.4APDF | Integrated Safety Management Policy | Archive | AU - Office of Environment, Health, Safety and Security | Apr 25, 2011 |
| DOE P 450.4A Chg 1 (MinChg)PDF | Integrated Safety Management Policy | Current | EH - Office of Environment, Health, Safety and Security | Apr 25, 2011 |
| DOE P 450.5PDF | Line Environment, Safety and Health Oversight | Archive | DP - Office of Defense Programs | Jun 26, 1997 |
| DOE P 450.6PDF | Secretarial, Policy Statement Environment, Safety and Health | Archive | EH - Office of Environment, Safety and Health | Apr 14, 1998 |
| DOE P 450.7PDF | Environment, Safety and Health (ESH) Goals | Archive | HS - Office of Health, Safety and Security | Aug 2, 2004 |
| DOE P 451.1PDF | National Environmental Policy Act Compliance Program | Current | GC - Office of General Counsel | Dec 21, 2017 |
| DOE P 454.1PDF | Use of Institutional Controls | Archive | HS - Office of Health, Safety and Security | Apr 9, 2003 |
| DOE P 454.1 Chg 1 (Admin Chg)PDF | Use of Institutional Controls | Current | EH - Office of Environment, Health, Safety and Security | Apr 9, 2003 |
| DOE P 455.1PDF | Use of Risk-Based End States | Archive | EM - Office of Environmental Management | Jul 15, 2003 |
| DOE P 456.1PDF | Secretarial Policy Statement on Nanoscale Safety | Archive | AU - Office of Environment, Health, Safety and Security | Sep 15, 2005 |
| DOE P 456.1 (Cert Memo)PDF | Certification for DOE P 456.1 | Archive | HS - Office of Health, Safety and Security | Oct 2, 2014 |
| DOE P 456.1 Chg 1 (AdminChg)PDF | Secretarial Policy Statement on Nanoscale Safety | Current | EH - Office of Environment, Health, Safety and Security | Sep 15, 2015 |
| DOE P 470.1PDF | Integrated Safeguards and Security Management (ISSM) Policy | Archive | HS - Office of Health, Safety and Security | May 8, 2001 |
| DOE P 470.1APDF | Safeguards and Security Program | Archive | HS - Office of Health, Safety and Security | Dec 29, 2010 |
| DOE P 470.1BPDF | Safeguards and Security Program | Current | EH - Office of Environment, Health, Safety and Security | Feb 10, 2016 |
| DOE P 481.1PDF | DOE's Policy Regarding Laboratories, Plants and Sites Engaging in Strategic Partnership Projects with Other Federal Agencies, Independent Organizations, and the Private Sector | Current | MA - Office of Management | Dec 17, 2014 |